The drug is dispersed in saliva and swallowed with little or no water. ODT may be used without the addition of water. ODT have been developed to disintegrate rapidly in the saliva after oral administration. Targeted-release dosage forms may have either immediate- or extended-release characteristics. A dosage form that releases drug at or near the intended physiologic site of action (see Chapter 18). Enteric-coated dosage forms are common delayed-release products (eg, enteric-coated aspririn and other NSAID products). An initial portion may be released promptly after administration. A dosage form that releases a discrete portion or portions of drug at a time other than promptly after administration. Examples of extended-release dosage forms include controlled-release, sustained-release, and long-acting drug products.ĭelayed-release drug products. ![]() A dosage form that allows at least a twofold reduction in dosage frequency as compared to that drug presented as an immediate-release (conventional) dosage form.
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